Anti Estrogens

Anti-estrogens are substances commonly used in bodybuilding to reduce or eliminate the effects of estrogen in the body. Estrogen is a hormone present in both men and women, but men have much lower levels of it. In bodybuilding, high levels of estrogen can have negative effects such as water retention, gynecomastia (breast tissue growth in men), and reduced muscle definition.

Anti-estrogens work by blocking the effects of estrogen or reducing its production. There are different types of anti-estrogens commonly used in bodybuilding including:

1. Selective estrogen receptor modulators (SERMs) such as tamoxifen and clomiphene. These drugs bind to estrogen receptors and block the effect of estrogen.
2. Aromatase inhibitors (AIs) such as anastrozole, letrozole and exemestane. These drugs reduce the production of estrogen by inhibiting the enzyme called aromatase which converts testosterone to estrogen.
3. Estrogen receptor down-regulators (ERDs) such as fulvestrant. This drug blocks the estrogen receptors and reduces their numbers, reducing the overall effect of estrogen in the body.

Anti-estrogens are used in bodybuilding during and after steroid cycles to reduce or eliminate estrogenic side effects. They are also used in post-cycle therapy to help restore natural testosterone production. It is important to use these drugs under the supervision of a medical professional as they can have side effects such as hot flashes, mood changes, and decreased libido.